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Glue vs Laser vs RFA: Best Varicose Vein Treatment?

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18-October-2025 Category: Diagnosis and Treatment

Varicose veins are more than a cosmetic issue — they are a medical condition that can cause aching, heaviness, swelling, cramps, skin discolouration, and, in advanced cases, ulcers or blood clots. If left untreated, the symptoms can worsen, affecting both health and quality of life.
The good news is that modern vein treatments are minimally invasive, safe, and highly effective. At Avis Vascular Centre, we specialise in three advanced options — Medical Glue Closure, Endovenous Laser Ablation (EVLA), and Radiofrequency Ablation (RFA). All three are walk-in/walk-out procedures, but each has its own strengths.

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Medical Glue Closure – The Needle-and-Done Solution

How it works: Using a thin catheter, a specially formulated medical adhesive is placed inside the diseased vein. The glue seals the vein instantly, and blood flow naturally reroutes to healthier veins.
Why choose it:
No heat, no multiple injections Usually no need for compression stockings Resume normal activity almost immediately Minimal discomfort during and after the procedure Best for: Patients seeking the least invasive option, especially those sensitive to injections or who cannot wear compression stockings due to lifestyle or skin conditions.

Confused about treatment options? Our experts will guide you step by step.

Endovenous Laser Ablation (EVLA) – Precision with Proven Results

How it works: A laser fibre is inserted into the affected vein under ultrasound guidance. Laser energy is delivered to heat and seal the vein walls, closing it permanently.
Why choose it:
Over 20 years of clinical success worldwide
Excellent long-term closure rates above 95%
Quick recovery — usually within 24–48 hours
Highly precise for targeted treatment
Considerations: Requires local anaesthesia along the vein’s length and typically one week of compression stockings to optimise results.
Best for: Patients with large, straight veins where maximum precision is needed for complete closure.


Radiofrequency Ablation (RFA) – Gentle Heat, Lasting Relief

How it works: A fine catheter delivers controlled radiofrequency energy to the vein wall. The heat causes the vein to collapse and seal shut, while surrounding tissues remain protected.
Why choose it:
Less post-procedure discomfort than older heat-based methods
Procedure time usually under 45 minutes
Quick return to normal activities, often the next day
Considerations: Like EVLA, it requires local anaesthesia and short-term compression stockings.
Best for: Patients who want a comfortable thermal treatment with proven long-term results.


Choosing the Right Option

Your ideal treatment depends on the size and shape of your veins, your medical history, and your personal comfort preferences. Glue offers the ultimate convenience with no heat or stockings. Laser is ideal for larger, straighter veins needing precision. RFA provides a gentle heat-based solution with excellent patient comfort.

At Avis Vascular Centre, we use detailed ultrasound vein mapping to select the treatment that best suits you — ensuring safe, effective, and lasting results.


Frequently Asked
Questions

For any unanswered questions, reach out to our support team via email. We’ll respond as soon as possible to assist you.

For Enquiry
info@avisvascularcentre.com
+ 91 80089 49900

How does glue-based varicose vein treatment differ from laser or radiofrequency methods?

Glue-based treatment closes the affected vein using a medical adhesive instead of heat. Unlike laser or radiofrequency procedures, it does not require multiple injections of tumescent anaesthesia along the vein. This makes the procedure more comfortable, reduces the risk of heat-related nerve injury, and allows for a quicker return to daily activities.

Is the medical glue used inside the vein safe for the body in the long term?

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Yes, the adhesive used in glue-based vein closure is a specially formulated medical-grade cyanoacrylate that has been extensively studied and approved for vascular use. It has been safely used worldwide for over a decade and is also applied in other surgical fields. Once the vein is sealed, the body gradually absorbs the treated vein while the glue remains inert and does not circulate in the bloodstream.

Can glue treatment cause allergic reactions or serious side effects?

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Serious reactions are rare. A small number of patients may experience mild inflammation, tenderness, or a localized reaction along the treated vein, which usually settles with simple medication. True allergic reactions are extremely uncommon, especially when the procedure is performed after proper evaluation by a vascular specialist.

Will the glue travel to other parts of the body or affect blood circulation?

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No, the adhesive is delivered in controlled amounts and hardens instantly inside the targeted vein. It does not travel to the heart or lungs. Blood circulation actually improves after the procedure because blood is redirected from the diseased vein into healthy veins that function normally.

Is glue-based treatment suitable for elderly patients or those with medical conditions?

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Glue closure is often an excellent option for elderly patients or those with conditions such as diabetes, heart disease, or sensitivity to anaesthesia. Since it does not involve heat, large injections, or general anaesthesia, it is considered a low-stress procedure when performed after proper medical assessment.